Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519918 | 0.86 | CYP3A4 (0.50) | TRPM4ALOX5MEN1KMT2ACYP3A4 | |
| SCHEMBL25824624 | 0.76 | AHR (0.45) | MEN1KMT2ATDP1PDE4DKDM4E | |
| SCHEMBL30176902 | 0.74 | MAPT (0.60) | ALOX5MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL28380621 | 0.74 | MAPT (0.60) | ALOX5MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25022558 | 0.72 | GPR84 (0.42) | ALOX5MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL25465685 | 0.72 | MAOB (0.43) | ALOX5MEN1KMT2ATDP1POLB | |
| SCHEMBL14576139 | 0.71 | ALDH1A1 (0.51) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL508755 | 0.70 | TRPM4 (1.00) | TRPM4ALOX5MAPTTDP1POLB | |
| SCHEMBL29399180 | 0.70 | TRPM4 (1.00) | TRPM4ALOX5MAPTTDP1POLB | |
| SCHEMBL9080220 | 0.70 | AKR1C3 (0.72) | ALOX5MEN1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358459-B | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-112358459-A | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2021-02-12 | — | — | CN | disclosed |