Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519499 | 0.83 | RXRA (0.40) | ALDH1A1L3MBTL1TDP1LIPEMAPT | |
| SCHEMBL28521420 | 0.83 | ALDH1A1 (0.45) | MRGPRX4LMNAALDH1A1L3MBTL1LIPE | |
| SCHEMBL28521446 | 0.80 | NPC1 (0.39) | ALDH1A1L3MBTL1TDP1KMT2AFFAR1 | |
| SCHEMBL28512482 | 0.79 | ENPP2 (0.42) | DAOL3MBTL1MAPTENPP2 | |
| SCHEMBL28520513 | 0.79 | CA1 (0.41) | DAOLMNAALDH1A1L3MBTL1HDAC6 | |
| SCHEMBL28520033 | 0.77 | MAOB (0.41) | MRGPRX4DAOLMNAHDAC1HDAC6 | |
| SCHEMBL15332082 | 0.74 | LMNA (0.43) | MRGPRX4DAOLMNAALDH1A1L3MBTL1 | |
| SCHEMBL28520517 | 0.71 | ACHE (0.44) | LMNAALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL28529096 | 0.71 | NPC1 (0.42) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL28521411 | 0.70 | ENPP2 (0.51) | MRGPRX4LMNAALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |