Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.58 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855315 | 0.96 | KDM4E (0.65) | CCR1KDM4EALDH1A1HPGDDDR1 | |
| SCHEMBL2860213 | 0.92 | KDM4E (0.73) | CCR1KDM4EALDH1A1HPGDDDR1 | |
| SCHEMBL2855580 | 0.90 | CCR1 (0.62) | CCR1KDM4EALDH1A1DDR1MAPK11 | |
| SCHEMBL2856181 | 0.90 | CCR1 (0.56) | CCR1KDM4EALDH1A1DDR1MAPK11 | |
| SCHEMBL2850153 | 0.90 | KDM4E (0.63) | CCR1KDM4EALDH1A1HPGDDDR1 | |
| SCHEMBL2852896 | 0.90 | KDM4E (0.63) | CCR1KDM4EALDH1A1HPGDDDR1 | |
| SCHEMBL2853014 | 0.89 | KDM4E (0.60) | CCR1KDM4EALDH1A1DDR1MAPK11 | |
| SCHEMBL2859933 | 0.89 | CCR1 (0.80) | CCR1HPGDMAPTMEN1KMT2A | |
| SCHEMBL2862276 | 0.88 | CCR1 (0.70) | CCR1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL2855565 | 0.87 | CCR1 (0.66) | CCR1KDM4EALDH1A1MAPTTRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |