Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DDT | P30046 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861171 | 0.91 | CCR1 (0.69) | CCR1NPSR1KDM4EALDH1A1HPGD | |
| SCHEMBL2860538 | 0.91 | KDM4E (0.61) | CCR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL2859933 | 0.89 | CCR1 (0.80) | CCR1HSP90AA1MAPTNPSR1HPGD | |
| SCHEMBL2852015 | 0.88 | CCR1 (0.63) | CCR1HSP90AA1MAPTNPSR1TRPC3 | |
| SCHEMBL2854508 | 0.85 | CCR1 (0.62) | CCR1HSP90AA1MAPTNPSR1KDM4E | |
| SCHEMBL2854425 | 0.85 | CCR1 (0.60) | CCR1MAPTTRPC3KDM4EALDH1A1 | |
| SCHEMBL2854543 | 0.84 | CCR1 (0.54) | CCR1HSP90AA1MAPTNPSR1DDT | |
| SCHEMBL2855565 | 0.84 | CCR1 (0.66) | CCR1HSP90AA1MAPTNPSR1TRPC3 | |
| SCHEMBL2855315 | 0.83 | KDM4E (0.65) | CCR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL2852818 | 0.83 | NPC1 (0.50) | CCR1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |