Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891740 | 0.80 | DRD2 (0.58) | DRD2DRD3HTR2CMTNR1AMTNR1B | |
| SCHEMBL12891741 | 0.80 | DRD2 (0.58) | DRD2DRD3HTR2CMTNR1AMTNR1B | |
| SCHEMBL12993416 | 0.78 | DRD2 (0.57) | DRD2DRD3HTR2CHTR2AHTR2B | |
| SCHEMBL28447625 | 0.75 | DRD2 (0.41) | DRD2DRD3HTR2CMTNR1AMTNR1B | |
| SCHEMBL28871332 | 0.72 | DRD2 (0.51) | DRD2DRD3HTR2CMTNR1AMTNR1B | |
| SCHEMBL25521579 | 0.70 | DRD2 (0.33) | DRD2DRD3 | |
| SCHEMBL4181488 | 0.70 | NPC1 (0.47) | DRD2DRD3HTR2CMTNR1AMTNR1B | |
| SCHEMBL4170720 | 0.70 | DRD2 (0.47) | DRD2DRD3HTR2CHTR2AHTR2B | |
| SCHEMBL19281913 | 0.69 | DRD2 (0.62) | DRD2DRD3MTNR1AMTNR1B | |
| SCHEMBL4597831 | 0.68 | DRD2 (0.52) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | claimed |
| CN-107652230-B | Synthesis method of 2-methoxy-7, 8-dihydroquinoline-6 (5H) -ketone | 上海亚兴生物医药科技有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-115232138-B | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-107652230-B | Synthesis method of 2-methoxy-7, 8-dihydroquinoline-6 (5H) -ketone | 上海亚兴生物医药科技有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-107652230-B | Synthesis method of 2-methoxy-7, 8-dihydroquinoline-6 (5H) -ketone | 上海亚兴生物医药科技有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-107652230-B | Synthesis method of 2-methoxy-7, 8-dihydroquinoline-6 (5H) -ketone | 上海亚兴生物医药科技有限公司 | 2021-01-05 | — | — | CN | disclosed |