Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891741 | 0.76 | DRD2 (0.58) | DRD2DRD3PDE10AHTR2CDRD1 | |
| SCHEMBL12891740 | 0.76 | DRD2 (0.58) | DRD2DRD3PDE10AHTR2CDRD1 | |
| SCHEMBL12993416 | 0.75 | DRD2 (0.57) | DRD2DRD3HTR2CHTR2AHTR2B | |
| SCHEMBL28520383 | 0.72 | DRD2 (0.58) | DRD2DRD3PDE10AHTR2CDRD1 | |
| SCHEMBL4181488 | 0.67 | NPC1 (0.47) | DRD2DRD3HTR2CDRD1HTR2A | |
| SCHEMBL4170720 | 0.67 | DRD2 (0.47) | DRD2DRD3HTR2CDRD1HTR2A | |
| SCHEMBL7899159 | 0.66 | DRD2 (0.41) | DRD2DRD3HTR2CDRD1HTR2A | |
| SCHEMBL28935814 | 0.64 | DRD2 (0.45) | DRD2DRD3PDE10AHTR2CHTR2A | |
| SCHEMBL30207715 | 0.64 | DRD2 (0.45) | DRD2DRD3PDE10AHTR2CHTR2A | |
| SCHEMBL29730608 | 0.63 | DRD2 (0.43) | DRD2DRD3HTR2CDRD1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232138-B | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115232138-B | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232138-A | Huperzine A intermediate and nontoxic synthesis process of raw materials thereof | 杭州师范大学 | 2022-10-25 | — | — | CN | disclosed |