Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.80 |
| ▸ | POLB | P06746 | 9/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.80 |
| ▸ | GLA | P06280 | 5/20 | 0.80 |
| ▸ | HPGD | P15428 | 5/20 | 0.80 |
| ▸ | GAA | P10253 | 4/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | ESR1 | P03372 | 1/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | RECQL | P46063 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703130 | 0.89 | KDM4E (1.00) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL116036 | 0.89 | KDM4E (1.00) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4472928 | 0.87 | KDM4E (0.97) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13312200 | 0.86 | KDM4E (0.80) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL4460070 | 0.86 | KDM4E (0.80) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL23722921 | 0.80 | CACNA1B (0.75) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL3331112 | 0.80 | UBE2I (0.78) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL379807 | 0.79 | LMNA (0.76) | KDM4EPOLBMEN1KMT2ALMNA | |
| SCHEMBL29586433 | 0.79 | LMNA (0.76) | KDM4EPOLBMEN1KMT2ALMNA | |
| SCHEMBL30544606 | 0.79 | L3MBTL1 (0.80) | KDM4EPOLBALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321571-B | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2022-06-03 | — | — | CN | claimed |
| CN-112321571-A | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2021-02-05 | — | — | CN | claimed |
| CN-112321571-B | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112321571-B | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112321571-B | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112321571-A | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-112321571-A | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2021-02-05 | — | — | CN | disclosed |
| CN-112321571-A | 2-furan-quinoline-4-formamide compound and application thereof | 浙江工业大学 | 2021-02-05 | — | — | CN | disclosed |