Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527102 | 0.92 | CALCRL (0.35) | FFAR2RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL28518933 | 0.90 | FFAR2 (0.41) | FFAR2RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL28523802 | 0.89 | RIPK1 (0.48) | FFAR2RIPK1KDM4E | |
| SCHEMBL20835577 | 0.88 | FFAR2 (0.51) | FFAR2RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL21094084 | 0.86 | FFAR2 (0.42) | FFAR2RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL28534271 | 0.82 | ABCB1 (0.44) | FFAR2RIPK1 | |
| SCHEMBL28528408 | 0.82 | FFAR2 (0.36) | FFAR2RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL2587508 | 0.82 | FFAR2 (0.38) | FFAR2RIPK1CHRM2CHRM1CHRM3 | |
| SCHEMBL28907091 | 0.82 | CNR1 (0.37) | FFAR2DPP4MAPTMEN1KMT2A | |
| SCHEMBL20835929 | 0.82 | FFAR2 (0.44) | FFAR2RIPK1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |