SCHEMBL375726

SCHEMBL375726

CCC(OCC1CO1)[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329862 0.88 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL12079239 0.84 LMNA (0.33) ALDH1A1
SCHEMBL10415274 0.81 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL285219 0.81 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3462781 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL1469861 0.78 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL1035031 0.77 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3742107 0.77 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL2883599 0.75 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL15513608 0.75 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2107077-B1 Polyether alcohols containing organosiloxane groups by means of alkoxylation of epoxide-functional (poly)organosiloxanes on double metal cyanide (DMC) catalysts and method for their production EVONIK GOLDSCHMIDT GMBH (DE) 2012-01-25 EP disclosed
EP-2107077-A1 New polyether alcohols containing organosiloxane groups by means of alkoxylisation of epoxide functional (poly) organosiloxanes to double metal cyanide (DMC) catalysts and method for its production Evonik Goldschmidt GmbH (DE) 2009-10-07 EP disclosed
EP-0702686-B1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY CLARK CO (US) 2001-09-05 EP disclosed
US-5854147-A Non-woven web containing antimicrobial siloxane quaternary ammonium salts KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-12-29 US disclosed
US-5853641-A Method for preparing polyolefin fibers containing antimicrobial siloxane quarternary ammonium salts KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-12-29 US disclosed
US-5853883-A Polyolefin fibers containing antimicrobial siloxane quaternary ammonium salts KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-12-29 US disclosed
US-5777010-A BLEND WITH THERMOPLASTIC POLYOLEFIN KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-07-07 US disclosed
EP-0760821-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1997-03-12 EP disclosed
US-5569732-A TRISILOXANE KIMBERLY-CLARK CORPORATION (US) 1996-10-29 US disclosed
US-5567372-A Method for preparing a nonwoven web containing antimicrobial siloxane quaternary ammonium salts KIMBERLY-CLARK CORPORATION (US) 1996-10-22 US disclosed
EP-0702686-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1996-03-27 EP disclosed
WO-1995032977-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1995-12-07 WO disclosed
WO-1994029325-A1 ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS KIMBERLY-CLARK CORPORATION (US) 1994-12-22 WO disclosed