Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516880 | 0.75 | F2 (0.37) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL28785424 | 0.75 | F2 (0.37) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5230088 | 0.74 | RAPGEF4 (0.42) | F2PRSS1PRSS2PRSS3CA1 | |
| Hydroxyamine SCHEMBL259333 | 0.74 | CA1 (0.54) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL23788 | 0.74 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10846507 | 0.74 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL7930818 | 0.74 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| Ammonia Solution, Strong SCHEMBL5999943 | 0.74 | CA1 (0.58) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5232759 | 0.73 | RAPGEF4 (0.38) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL5234368 | 0.73 | LMNA (0.41) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776522-B | Substituted heteroaryl compounds, compositions and uses thereof | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |