Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850458 | 0.82 | MAPT (0.56) | MAPTKMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2850317 | 0.81 | KDM1A (0.58) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2858757 | 0.79 | MAPT (0.60) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL26673838 | 0.79 | MAPT (0.51) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13974535 | 0.77 | ADORA2A (0.49) | MEN1KMT2AKDM4ERAB9AHPGD | |
| SCHEMBL2857557 | 0.76 | BRPF1 (0.51) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL26673937 | 0.75 | KCNK3 (0.60) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL26674014 | 0.75 | KCNK3 (0.60) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5924153 | 0.75 | KDM1A (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL28399454 | 0.74 | KCNK3 (0.51) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |