Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 4/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850458 | 0.81 | MAPT (0.56) | KCNK3KCNK9RXFP1MAPTKMT2A | |
| SCHEMBL2852141 | 0.80 | JAK2 (0.56) | GAA | |
| SCHEMBL28399454 | 0.77 | KCNK3 (0.51) | BRPF1BRD4KCNK3KCNK9RXFP1 | |
| SCHEMBL28398322 | 0.77 | MAPT (0.59) | BRPF1BRD4KCNK3KCNK9RXFP1 | |
| SCHEMBL2858757 | 0.77 | MAPT (0.60) | KCNK3KCNK9RXFP1MAPTKMT2A | |
| SCHEMBL26673838 | 0.77 | MAPT (0.51) | BRPF1BRD4KCNK3KCNK9RXFP1 | |
| SCHEMBL5867557 | 0.76 | KCNK3 (0.50) | BRPF1BRD4KCNK3KCNK9RXFP1 | |
| SCHEMBL2852245 | 0.76 | MAPT (0.53) | BRPF1BRD4KCNK3KCNK9RXFP1 | |
| SCHEMBL15408194 | 0.76 | KMT2A (0.64) | KCNK3KCNK9RXFP1MAPTKMT2A | |
| SCHEMBL20673246 | 0.74 | ADCY1 (0.56) | MAPTKMT2AMEN1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |