Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | TCF4 | P15884 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28517900 | 0.98 | LMNA (0.60) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13452606 | 0.85 | HTT (0.54) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL22355728 | 0.84 | LMNA (0.50) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL19223061 | 0.83 | L3MBTL1 (0.57) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28528222 | 0.83 | LMNA (0.43) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28528265 | 0.82 | L3MBTL1 (0.56) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28524388 | 0.82 | TAS2R8 (0.44) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28531079 | 0.82 | SCD (0.47) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28523096 | 0.82 | EPHB4 (0.44) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28907455 | 0.81 | MAPT (0.44) | LMNAMAPTALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |