Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 20/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384069 | 0.84 | STS (1.00) | STSCA1CA2CA9ESR1 | |
| SCHEMBL3384071 | 0.84 | STS (1.00) | STSCA1CA2CA9ESR1 | |
| SCHEMBL2849377 | 0.83 | STS (0.66) | STSCA2CA9 | |
| SCHEMBL7177976 | 0.81 | STS (0.74) | STSCA1CA2CA9ESR1 | |
| SCHEMBL1258790 | 0.81 | STS (0.65) | STSCA2CA9 | |
| SCHEMBL2163618 | 0.80 | SHBG (0.68) | STSESR1ESR2 | |
| SCHEMBL5165430 | 0.79 | STS (0.74) | STSCA1CA2CA9ESR1 | |
| SCHEMBL2849680 | 0.79 | STS (0.47) | STSCA1CA2CA9ESR1 | |
| SCHEMBL5168699 | 0.78 | STS (0.59) | STSCA1CA2CA9ESR1 | |
| Emate SCHEMBL6370815 | 0.78 | STS (1.00) | STSCA1CA2CA9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594884-A1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004074308-A1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | WO | claimed |
| EP-1594884-B1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | STERIX LTD (GB) | 2010-01-13 | — | — | EP | disclosed |
| EP-1594884-A1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-11-16 | — | — | EP | disclosed |
| EP-1594884-A1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074308-A1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004074308-A1 | ANTITUMORAL 18A-HOMOESTRA-1,3,5(10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | WO | disclosed |