Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674956 | 0.84 | KAT8 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11036114 | 0.83 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28972443 | 0.82 | ASPH (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6931488 | 0.82 | NOS2 (0.55) | NOS2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3719445 | 0.78 | PPARA (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9488515 | 0.77 | NOS2 (0.58) | NOS2NOS3TLR8ALDH1A1 | |
| SCHEMBL1577580 | 0.77 | KDM5B (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14836066 | 0.77 | PPARA (0.60) | KAT8PPARARARBPPARGRARA | |
| SCHEMBL3662660 | 0.77 | PPARA (0.60) | KAT8PPARARARBPPARGRARA | |
| SCHEMBL14836443 | 0.77 | PPARA (0.60) | KAT8PPARARARBPPARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981795-B | Method for preparing 2-aminoacyl isonicotinic acid by using methyl 2-cyanoisonicotinate | 武汉世纪久海检测技术有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-110981795-B | Method for preparing 2-aminoacyl isonicotinic acid by using methyl 2-cyanoisonicotinate | 武汉世纪久海检测技术有限公司 | 2021-02-12 | — | — | CN | disclosed |