SCHEMBL28523255

SCHEMBL28523255

FC(F)(F)C(F)(F)C(Br)Br

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559527 0.77 LMNA (0.35) ALDH1A1HSD17B10
SCHEMBL1019199 0.74 LMNA (0.40) ALDH1A1HSD17B10
SCHEMBL1019193 0.69 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL6623945 0.69 ALDH1A1 (0.39) ALDH1A1HSD17B10
SCHEMBL8899596 0.67
SCHEMBL16986345 0.67
SCHEMBL5907232 0.65
SCHEMBL7072939 0.64
SCHEMBL3137832 0.64
SCHEMBL11672625 0.64 ALDH1A1 (0.33) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108101739-B Method for continuously preparing 3,3, 3-trifluoro-1, 2-propanediol 西安近代化学研究所 2021-04-13 CN disclosed
CN-108084143-B Method for continuously preparing 4-trifluoromethyl ethylene carbonate 西安近代化学研究所 2021-02-26 CN disclosed
CN-108178752-B Method for preparing 3,3, 3-trifluoropropene carbonate and 3,3, 3-trifluoro-1, 2-propylene glycol in co-production mode 西安近代化学研究所 2021-02-23 CN disclosed