Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405507 | 0.87 | TAAR1 (0.48) | TAAR1ACACBHDAC6KDM4E | |
| SCHEMBL16785094 | 0.85 | AOC3 (0.47) | ACACBACACA | |
| SCHEMBL30674018 | 0.85 | L3MBTL1 (0.40) | L3MBTL1GPR119NAMPTKDM4ELMNA | |
| SCHEMBL21527996 | 0.84 | POLB (0.46) | L3MBTL1GPR119NAMPT | |
| SCHEMBL29172479 | 0.82 | L3MBTL1 (0.39) | L3MBTL1ACACBACACAGPR119NAMPT | |
| SCHEMBL25999569 | 0.82 | GPR119 (0.41) | L3MBTL1HDAC6GPR119NAMPTMAPT | |
| SCHEMBL29172447 | 0.82 | SIGMAR1 (0.44) | HDAC6GPR119 | |
| SCHEMBL20425077 | 0.81 | TAAR1 (0.47) | TAAR1HDAC6GPR119KDM4EMAPT | |
| SCHEMBL20552595 | 0.81 | OGA (0.44) | L3MBTL1ACACBGPR119NAMPTKDM4E | |
| SCHEMBL30405421 | 0.80 | TAAR1 (0.55) | TAAR1HDAC6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368289-B | C26-linked rapamycin analogues as MTOR inhibitors | 锐新医药公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-115916194-A | Methods for delaying, preventing and treating acquired resistance to RAS inhibitors | 锐新医药公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-112771054-A | C40-, C28-and C-32-linked rapamycin analogs as mTOR inhibitors | 锐新医药公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-112368289-A | C26-linked rapamycin analogs as MTOR inhibitors | 锐新医药公司 | 2021-02-12 | — | — | CN | disclosed |