SCHEMBL2857308

SCHEMBL2857308

CCCCSc1cc2c(cc1OCCCCCCCCCCCCCCCCCC[Si](OC)(OC)OC)c1cc(SCCCC)c(SCCCC)cc1c1cc(SCCCC)c(SCCCC)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 1/20 0.35
▸ CNR2 P34972 1/20 0.34
▸ LMNA P02545 4/20 0.33
▸ SRC P12931 1/20 0.33
▸ PTGS2 P35354 3/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ HTT P42858 2/20 0.32
▸ NSD2 O96028 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ CYSLTR2 Q9NS75 1/20 0.31
▸ CYSLTR1 Q9Y271 1/20 0.31
▸ SMPD1 P17405 4/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866418 0.96 CNR2 (0.38) CNR2LMNASRCPTGS2NPSR1
SCHEMBL2863459 0.94 CNR2 (0.38) CNR2LMNASRCPTGS2NPSR1
SCHEMBL2860211 0.92 PDE3B (0.36) ARCNR2LMNANPSR1MAPT
SCHEMBL2858934 0.91 CNR2 (0.35) ARCNR2LMNAPTGS2HTT
SCHEMBL2860571 0.88 LMNA (0.39) ARLMNAPTGS2NPSR1MAPT
SCHEMBL2852351 0.87 CNR2 (0.39) CNR2LMNAPTGS2NPSR1MAPT
SCHEMBL2861736 0.86 CNR2 (0.35) ARCNR2LMNAPTGS2HTT
SCHEMBL2859248 0.85 LMNA (0.42) LMNAPTGS2NPSR1MAPTHTT
SCHEMBL2860136 0.85 CNR2 (0.39) CNR2LMNAPTGS2NPSR1MAPT
SCHEMBL2864266 0.83 CNR2 (0.35) CNR2LMNAPTGS2NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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