Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.54 |
| ▸ | AURKA | O14965 | 5/20 | 0.53 |
| ▸ | CCNC | P24863 | 2/20 | 0.52 |
| ▸ | CDK8 | P49336 | 2/20 | 0.52 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.52 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GMPS | P49915 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531052 | 0.83 | FYN (0.56) | FYNSRCEGFRAURKACCNC | |
| SCHEMBL5499111 | 0.78 | SRC (0.71) | FYNSRCEGFRAURKACCNC | |
| SCHEMBL8548720 | 0.77 | HTT (0.69) | FYNSRCEGFRCCNCCDK8 | |
| SCHEMBL157421 | 0.77 | NFKB1 (0.63) | FYNSRCEGFRAURKACCNC | |
| SCHEMBL29350229 | 0.77 | NFKB1 (0.63) | FYNSRCEGFRAURKACCNC | |
| SCHEMBL5496069 | 0.76 | SRC (0.68) | FYNSRCEGFRAURKACCNC | |
| SCHEMBL8543007 | 0.76 | HTT (0.77) | EGFRAURKACCNCCDK8CDKN1A | |
| SCHEMBL28530926 | 0.74 | CCNC (0.57) | FYNSRCEGFRCCNCCDK8 | |
| SCHEMBL8542891 | 0.74 | HTT (0.54) | FYNSRCEGFRAURKACCNC | |
| SCHEMBL12297970 | 0.73 | RNF4 (0.65) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209875-B | 6-amino-4- (4-phenoxyphenethylamino) quinazoline derivative and preparation method and application thereof | 绍兴文理学院 | 2021-11-30 | — | — | CN | disclosed |
| CN-112209875-A | 6-amino-4- (4-phenoxyphenethylamino) quinazoline derivative and preparation method and application thereof | 绍兴文理学院 | 2021-01-12 | — | — | CN | disclosed |