SCHEMBL6239972

SCHEMBL6239972

COc1ccccc1C1(O)Oc2ccccc2C(=O)C1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.42
KMT2A Q03164 1/20 0.40
CYP3A4 P08684 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
ALOX15 P16050 1/20 0.37
PDK2 Q15119 2/20 0.36
TOP1 P11387 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
CYP2C9 P11712 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
IDO1 P14902 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520578 0.70 GAA (0.43) CYP19A1KMT2ACYP3A4ALOX15KDM4E
SCHEMBL8484519 0.68 CYP19A1 (0.47) CYP19A1KMT2ACYP3A4ALOX15KDM4E
SCHEMBL364562 0.68 CYP3A4 (0.44) CYP19A1CYP3A4ALOX15CYP2C9IDO1
SCHEMBL3221182 0.68 CYP3A4 (0.44) CYP19A1KMT2ACYP3A4ALOX15CYP2C9
SCHEMBL3197529 0.68 CYP19A1 (0.46) CYP19A1KMT2ACYP3A4ALOX15KDM4E
SCHEMBL3221175 0.67 L3MBTL1 (0.44) CYP19A1KMT2ASIGMAR1MAPTL3MBTL1
SCHEMBL7520676 0.67 CRHBP (0.37) CYP19A1CYP3A4ALOX15PDK2MAPT
SCHEMBL27867196 0.67 MAPT (0.39) KMT2ACYP3A4CA1CA2CA7
SCHEMBL2118993 0.66 GNG2 (0.37) KMT2ACYP3A4ALOX15PDK2POLB
SCHEMBL28523565 0.66 KMT2A (0.44) KMT2ACYP3A4CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040038152-A1 Method for making printing plate by inkjet deposition on positive-working media CREO SRL (CA) 2004-02-26 US claimed
EP-1542871-A1 METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA Creo SRL (CA) 2005-06-22 EP disclosed
US-20040038152-A1 Method for making printing plate by inkjet deposition on positive-working media CREO SRL (CA) 2004-02-26 US disclosed
WO-2004007200-A1 METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA CREO SRL (CA) 2004-01-22 WO disclosed