Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523651 | 1.00 | KCNH2 (0.43) | KCNH2TACR1SIGMAR1SLC6A5KMT2A | |
| SCHEMBL28907976 | 0.89 | SMN1; SMN2 (0.42) | SIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28907975 | 0.89 | SMN1; SMN2 (0.42) | SIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28991793 | 0.84 | TACR1 (0.42) | KCNH2TACR1SIGMAR1SLC6A5LIPG | |
| SCHEMBL28545922 | 0.77 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL28522821 | 0.77 | TACR1 (0.47) | TACR1 | |
| SCHEMBL28528445 | 0.76 | CHRM5 (0.42) | HRH3 | |
| SCHEMBL28528446 | 0.76 | CHRM5 (0.42) | HRH3 | |
| SCHEMBL28523719 | 0.74 | TACR1 (0.46) | TACR1 | |
| SCHEMBL28519269 | 0.74 | ALDH1A1 (0.45) | KMT2AOPRD1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174869-A | Preparation method and medicinal application of N-phenylacetyl-2-hydroxymethyl pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | disclosed |