Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907976 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2GRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL28523651 | 0.89 | KCNH2 (0.43) | ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL28523650 | 0.89 | KCNH2 (0.43) | ALDH1A1MEN1KMT2ASIGMAR1 | |
| SCHEMBL28545922 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2 | |
| SCHEMBL28519269 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AGLAHPGD | |
| SCHEMBL28907061 | 0.76 | GRM5 (0.44) | GRM5 | |
| SCHEMBL28528446 | 0.75 | CHRM5 (0.42) | SMN1; SMN2 | |
| SCHEMBL28528445 | 0.75 | CHRM5 (0.42) | SMN1; SMN2 | |
| SCHEMBL28521347 | 0.73 | — | — | |
| SCHEMBL28991793 | 0.72 | TACR1 (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174869-B | Preparation method and medicinal application of N-phenylacetyl-2-hydroxymethyl pyrrolidine-2-formamide | 蔡霈 | 2023-04-25 | — | — | CN | disclosed |
| CN-112174869-A | Preparation method and medicinal application of N-phenylacetyl-2-hydroxymethyl pyrrolidine-2-formamide | 蔡霈 | 2021-01-05 | — | — | CN | disclosed |