Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632352 | 0.96 | DUT (0.45) | DUTPIK3CDKMT2AKDM4EALDH1A1 | |
| SCHEMBL21389245 | 0.91 | KMT2A (0.42) | DUTPIK3CDKMT2APDK2MEN1 | |
| SCHEMBL7508712 | 0.87 | KMT2A (0.38) | DUTPIK3CDKMT2APDK2SMN1; SMN2 | |
| SCHEMBL8865301 | 0.87 | DUT (0.44) | DUTKDM4EALDH1A1GLAGAA | |
| SCHEMBL9764243 | 0.81 | DUT (0.40) | DUTKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL6449914 | 0.81 | PIK3CD (0.43) | PIK3CDKMT2AALDH1A1TSHR | |
| SCHEMBL28437904 | 0.79 | DUT (0.46) | DUT | |
| SCHEMBL6161985 | 0.79 | DUT (0.43) | DUT | |
| SCHEMBL9739420 | 0.77 | PIK3CD (0.39) | DUTPIK3CDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1633091 | 0.77 | DUT (0.41) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |