SCHEMBL9764243

SCHEMBL9764243

CC(C)(C)[Si](C)(C)OCCN1CCC1=O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.40
NPC1 O15118 5/20 0.40
RAB9A P51151 5/20 0.40
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 1/20 0.33
BUB1 O43683 1/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21389245 0.90 KMT2A (0.42) DUTNPC1RAB9AMEN1KMT2A
SCHEMBL7508712 0.89 KMT2A (0.38) DUTNPC1RAB9AMEN1KMT2A
SCHEMBL8865301 0.89 DUT (0.44) DUTNPC1RAB9AGAAPOLB
SCHEMBL28523658 0.81 DUT (0.46) DUTNPC1RAB9AMEN1KMT2A
SCHEMBL21803341 0.81 DDB1 (0.42) DUTMEN1KMT2AGAABUB1
SCHEMBL20660200 0.80 DUT (0.39) DUT
SCHEMBL1632352 0.80 DUT (0.45) DUTRAB9AMEN1KMT2AGAA
SCHEMBL21389203 0.80 DUT (0.39) DUT
SCHEMBL9811322 0.78 MEN1 (0.35) DUTNPC1MEN1KMT2AGAA
SCHEMBL25283813 0.78 KDM4E (0.39) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119819228-B Continuous production device and method for penem drug intermediate 4-AA 济南大学 2025-05-27 CN claimed
CN-119819228-A Continuous production device and method for penem drug intermediate 4-AA 济南大学 2025-04-15 CN claimed
JP-58198492-A None JP disclosed
CN-119819228-B Continuous production device and method for penem drug intermediate 4-AA 济南大学 2025-05-27 CN disclosed
CN-119819228-A Continuous production device and method for penem drug intermediate 4-AA 济南大学 2025-04-15 CN disclosed
CN-1803807-A 4AA oxidizing synthesis method UNIV SHANGHAI JIAOTONG (CN) 2006-07-19 CN disclosed
EP-0255307-B1 PROCESS FOR THE SYNTHESIS OF PENEMS PFIZER INC. (US) 1991-12-04 EP disclosed
EP-0320497-A1 Substituted 2-thioxopenams, intermediates therefrom and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems MERCK & CO. INC. (US) 1989-06-14 EP disclosed
EP-0301877-A1 A method of deprotection of 3-amino azetidinones ELI LILLY AND COMPANY (US) 1989-02-01 EP disclosed
JP-S58198492-A NOVEL AZETIDINE DERIVATIVE AND ITS PREPARATION KOWA CO 1983-11-18 JP disclosed