Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852672 | 0.92 | MAPT (0.60) | MAPTMAPK14LMNAALDH1A1PKM | |
| SCHEMBL2853414 | 0.90 | MAPK14 (0.55) | MAPTMAPK14LMNAALDH1A1PKM | |
| SCHEMBL2856552 | 0.87 | MAPT (0.53) | MAPTLMNATSHRALDH1A1PKM | |
| SCHEMBL2860462 | 0.87 | MAPT (0.55) | MAPTMAPK14LMNAHTTALDH1A1 | |
| SCHEMBL2853491 | 0.87 | ALDH1A1 (0.55) | MAPTMAPK14LMNAALDH1A1PKM | |
| SCHEMBL2857236 | 0.86 | MAPT (0.54) | MAPTMAPK14LMNAALDH1A1PKM | |
| SCHEMBL2852439 | 0.86 | MAPT (0.56) | MAPTMAPK14LMNAALDH1A1PKM | |
| SCHEMBL2857246 | 0.85 | MAPT (0.57) | MAPTMAPK14LMNAALDH1A1PKM | |
| SCHEMBL2856261 | 0.83 | MAPT (0.56) | MAPTMAPK14LMNATSHRALDH1A1 | |
| SCHEMBL2859079 | 0.83 | MAPT (0.60) | MAPTLMNAHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |