Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850371 | 0.92 | MAPT (0.72) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2852672 | 0.90 | MAPT (0.60) | MAPTALDH1A1RAB9APOLBMAPK1 | |
| SCHEMBL2860462 | 0.85 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2853491 | 0.85 | ALDH1A1 (0.55) | MAPTALDH1A1RAB9APOLBMAPK1 | |
| SCHEMBL2857236 | 0.85 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2852439 | 0.84 | MAPT (0.56) | MAPTALDH1A1RAB9ANPC1POLB | |
| SCHEMBL2856552 | 0.84 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2857246 | 0.83 | MAPT (0.57) | MAPTALDH1A1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL2852391 | 0.83 | MAPT (0.52) | MAPTALDH1A1RAB9APOLBLMNA | |
| SCHEMBL2856261 | 0.82 | MAPT (0.56) | MAPTALDH1A1RAB9APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |