Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852672 | 0.93 | MAPT (0.60) | MAPTALDH1A1POLBLMNAPKM | |
| SCHEMBL2850541 | 0.90 | MAPT (0.58) | MAPTALDH1A1TP53GAARAB9A | |
| SCHEMBL2860462 | 0.88 | MAPT (0.55) | MAPTALDH1A1TP53LMNAPKM | |
| SCHEMBL2853491 | 0.88 | ALDH1A1 (0.55) | MAPTALDH1A1POLBLMNAPKM | |
| SCHEMBL2852391 | 0.87 | MAPT (0.52) | MAPTALDH1A1POLBLMNAPKM | |
| SCHEMBL2857236 | 0.87 | MAPT (0.54) | MAPTALDH1A1NPBWR1MCHR1LMNA | |
| SCHEMBL2852439 | 0.87 | MAPT (0.56) | MAPTALDH1A1POLBLMNAPKM | |
| SCHEMBL2857246 | 0.85 | MAPT (0.57) | MAPTALDH1A1LMNAPKMNR3C1 | |
| SCHEMBL2856261 | 0.84 | MAPT (0.56) | MAPTALDH1A1POLBLMNAPKM | |
| SCHEMBL2859079 | 0.84 | MAPT (0.60) | MAPTALDH1A1POLBTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |