Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1169601 | 0.94 | THRB (0.55) | THRBTSHRALDH1A1MGAMGAA | |
| Sulfuric Acid SCHEMBL1943128 | 0.92 | THRB (0.53) | THRBTSHRALDH1A1MGAMGAA | |
| Sulfuric Acid SCHEMBL1943127 | 0.92 | THRB (0.53) | THRBTSHRALDH1A1MGAMGAA | |
| Dimethylamine SCHEMBL321116 | 0.92 | THRB (0.57) | THRBTSHRALDH1A1MGAMGAA | |
| Dimethylamine SCHEMBL2982086 | 0.90 | THRB (0.55) | THRBTSHRALDH1A1MGAMGAA | |
| Dimethylamine SCHEMBL7516850 | 0.90 | THRB (0.55) | THRBTSHRALDH1A1MGAMGAA | |
| Sulfuric Acid SCHEMBL631032 | 0.88 | THRB (0.50) | THRBTSHRALDH1A1MGAMGAA | |
| Dimethylamine SCHEMBL4389426 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1MGAMGAA | |
| Acetic Acid SCHEMBL8023904 | 0.88 | THRB (0.53) | THRBTSHRALDH1A1MGAMGAA | |
| Dimethylamine SCHEMBL8665783 | 0.88 | THRB (0.53) | THRBTSHRALDH1A1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109971449-B | Supermolecular system polymer microgel for oil reservoir deep profile control and flooding and preparation method thereof | 聚盛绿能河北科技有限公司 | 2021-03-02 | — | — | CN | claimed |
| CN-109971449-B | Supermolecular system polymer microgel for oil reservoir deep profile control and flooding and preparation method thereof | 聚盛绿能河北科技有限公司 | 2021-03-02 | — | — | CN | disclosed |