Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852393 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPK1MAPTHPGDRAB9A | |
| SCHEMBL2856101 | 0.83 | HPGD (0.55) | ALDH1A1MAPK1MAPTHPGDCCR1 | |
| SCHEMBL2863421 | 0.81 | EPHX1 (0.46) | ALDH1A1MAPK1MAPTHPGDRAB9A | |
| SCHEMBL2856416 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAPTRAB9ANR4A3 | |
| SCHEMBL2855497 | 0.79 | MAPT (0.52) | ALDH1A1MAPK1MAPTCCR1RAB9A | |
| SCHEMBL2855394 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAPTRAB9ANR4A3 | |
| SCHEMBL2861197 | 0.78 | CCR1 (0.51) | ALDH1A1MAPTHPGDCYP2C9CYP2C19 | |
| SCHEMBL2854459 | 0.78 | CCR1 (0.54) | MAPTCCR1 | |
| SCHEMBL2856225 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPK1MAPTRAB9ANR4A3 | |
| SCHEMBL2856513 | 0.78 | TAAR1 (0.51) | ALDH1A1MAPK1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |