Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995027 | 0.84 | HPGD (0.57) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL2858114 | 0.84 | HPGD (0.57) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL2852403 | 0.83 | CACNA1G (0.43) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL3971476 | 0.80 | ALDH1A1 (0.58) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL2857376 | 0.79 | ALDH1A1 (0.67) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL3972889 | 0.78 | HPGD (0.51) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL2856222 | 0.78 | MAPT (0.67) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL3970328 | 0.78 | ALDH1A1 (0.55) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL4670702 | 0.77 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTMAPK1GAA | |
| SCHEMBL2855062 | 0.77 | CCR1 (0.65) | HPGDALDH1A1MAPTCCR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |