Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857467 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MAPTMAPK1MAPK14LMNA | |
| SCHEMBL2852508 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL2855497 | 0.85 | MAPT (0.52) | ALDH1A1MAPTMAPK1MAPK14TACR1 | |
| SCHEMBL2863421 | 0.84 | EPHX1 (0.46) | ALDH1A1MAPTMAPK1MAPK14LMNA | |
| SCHEMBL2855394 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1MAPK14LMNA | |
| SCHEMBL2857376 | 0.84 | ALDH1A1 (0.67) | ALDH1A1MAPTMAPK1MAPK14LMNA | |
| SCHEMBL2852393 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1MAPK14LMNA | |
| SCHEMBL2855564 | 0.82 | CNR1 (0.48) | ALDH1A1MAPTMAPK1MAPK14LMNA | |
| SCHEMBL2854459 | 0.81 | CCR1 (0.54) | MAPTMAPK14 | |
| SCHEMBL2852403 | 0.81 | CACNA1G (0.43) | ALDH1A1MAPTMAPK1LMNANR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |