Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458977 | 0.84 | OPRL1 (0.47) | OPRL1OPRM1OPRK1HDAC4OPRD1 | |
| SCHEMBL7815717 | 0.78 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL10060840 | 0.78 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL34468465 | 0.78 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL7737678 | 0.75 | OPRM1 (0.42) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL1109741 | 0.74 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL1724862 | 0.74 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL42581 | 0.73 | OPRL1 (0.52) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL13605139 | 0.72 | OPRL1 (0.61) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL16823462 | 0.72 | OPRL1 (0.45) | OPRL1OPRM1OPRK1OPRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358457-B | Method for synthesizing chiral endocyclic lactone | 武汉大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112358457-A | Method for synthesizing chiral endocyclic lactone | 武汉大学 | 2021-02-12 | — | — | CN | disclosed |