SCHEMBL7815717

SCHEMBL7815717

OC1(c2ccccc2)CC1

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 16/20 0.68
OPRM1 P35372 11/20 0.68
OPRK1 P41145 11/20 0.68
OPRD1 P41143 9/20 0.55
POLB P06746 1/20 0.53
SIGMAR1 Q99720 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060840 1.00 OPRL1 (0.68) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL13605139 0.92 OPRL1 (0.61) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL11762583 0.90 OPRL1 (0.59) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL1724862 0.89 OPRL1 (0.57) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL1109741 0.89 OPRL1 (0.57) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL60129 0.87 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL29195226 0.87 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
Ammonia Solution, Strong SCHEMBL29195223 0.87 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL1040024 0.87 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL16469256 0.87 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121717728-B Benzamide/benzenesulfonamide compound containing aryl butanone structure, and preparation method and application thereof YANTAI UNIVERSITY (CN) 2026-05-26 CN claimed
US-20250129116-A1 CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS UNIVERSITY OF SOUTH CAROLINA 2025-04-24 US claimed
CN-110294972-A A kind of ink 深圳TCL工业研究院有限公司 2019-10-01 CN claimed
CN-121717728-B Benzamide/benzenesulfonamide compound containing aryl butanone structure, and preparation method and application thereof YANTAI UNIVERSITY (CN) 2026-05-26 CN disclosed
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2026-05-07 US disclosed
US-20260118361-A1 FLUOROGENIC BIOCONJUGATION OF CYCLOPROPANOL-BASED FLUOROPHORES FOR BIOLOGICAL APPLICATIONS UNIV SOUTH CAROLINA (US) 2026-04-30 US disclosed
US-12370194-B2 Metalloenzyme inhibitor compounds EIKONIZO THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
US-20250129116-A1 CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS UNIVERSITY OF SOUTH CAROLINA 2025-04-24 US disclosed
CN-116253677-B Method for synthesizing pyridine compound by utilizing micro-channel reaction device 南京工业大学 2025-01-28 CN disclosed
CN-118993956-A Preparation method of sulfonyl bridged 1, 7-dicarbonyl compound 安阳师范学院 2024-11-22 CN disclosed
CN-118978472-A Preparation method of indolone compound connected with gamma-ketosulfone structure 安阳师范学院 2024-11-19 CN disclosed
US-8975235-B2 Lysophosphatidic acid receptor antagonists INTERMUNE, INC. (US) 2015-03-10 US disclosed
US-8975235-B2 Lysophosphatidic acid receptor antagonists INTERMUNE, INC. (US) 2015-03-10 US disclosed
US-20130072449-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. (US) 2013-03-21 US disclosed
US-20130072449-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. (US) 2013-03-21 US disclosed
WO-2013025733-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS INTERMUNE, INC. (US) 2013-02-21 WO disclosed
EP-1144415-A2 FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS WARNER-LAMBERT COMPANY (US) 2001-10-17 EP disclosed
WO-2000042045-A2 FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS WARNER-LAMBERT COMPANY (US) 2000-07-20 WO disclosed
EP-0192638-A1 LEMON-YELLOW DIAZO COMPOSITIONS JAMES RIVER-GRAPHICS, INC. (US) 1986-09-03 EP disclosed
WO-1986001505-A1 LEMON-YELLOW DIAZO COMPOSITIONS JAMES RIVER GRAPHICS, INC. (US) 1986-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129116-A1 CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS CBR3, CBR1, BBOX1 OPRL1 2897/4885OPRM1 2318/4885OPRK1 1571/4885
US-20130072449-A1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS LPAR1, LPAR2, LPAR5 OPRL1 311/4885OPRM1 1387/4885OPRK1 700/4885
US-20260118361-A1 FLUOROGENIC BIOCONJUGATION OF CYCLOPROPANOL-BASED FLUOROPHORES FOR BIOLOGICAL APPLICATIONS QSOX1, CBR1, CBR3 OPRL1 589/4885OPRM1 905/4885OPRK1 893/4885
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC3, HDAC1 OPRL1 2077/4885OPRM1 1612/4885OPRK1 2584/4885
US-12370194-B2 Metalloenzyme inhibitor compounds HDAC6, HDAC1, HDAC2 OPRL1 4562/4885OPRM1 3279/4885OPRK1 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.