Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA7 | P43166 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544340 | 0.84 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28126806 | 0.82 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL39010 | 0.82 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5127002 | 0.82 | KDM4E (0.44) | ALDH1A1LCKTDP1HSD17B10KDM4E | |
| SCHEMBL256719 | 0.82 | TDP1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7627461 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TSHRPTGS2PRKCETDP1 | |
| SCHEMBL9768507 | 0.82 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27517848 | 0.81 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3873135 | 0.81 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27658957 | 0.81 | CA12 (0.55) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112656954-A | Lipid formulations for delivery of messenger RNA | 夏尔人类遗传性治疗公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-112618732-A | Lipid formulations for delivery of messenger RNA | 夏尔人类遗传性治疗公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-105813656-B | Lipid formulations for delivery of messenger RNA | 夏尔人类遗传性治疗公司 | 2021-01-15 | — | — | CN | disclosed |