Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.36 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257679 | 0.83 | HCAR2 (0.39) | ALDH1A1KDM4EHCAR2TSHRDCLRE1A | |
| SCHEMBL257240 | 0.83 | KDM4E (0.40) | POLBALDH1A1KDM4ECA12CA1 | |
| SCHEMBL28524315 | 0.82 | CA12 (0.52) | TDP1POLBL3MBTL1PRKCEALDH1A1 | |
| SCHEMBL7627461 | 0.79 | ALDH1A1 (0.57) | TDP1POLBL3MBTL1PRKCEKDM5A | |
| SCHEMBL5127002 | 0.79 | KDM4E (0.44) | TDP1POLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL256737 | 0.78 | DCLRE1B (0.40) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL24801286 | 0.77 | APEX1 (0.44) | TDP1ALDH1A1KDM4ECA12CA1 | |
| SCHEMBL14900060 | 0.76 | TDP1 (0.46) | TDP1POLBL3MBTL1PRKCEKDM5A | |
| SCHEMBL14900113 | 0.76 | POLB (0.51) | TDP1POLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11358475 | 0.74 | KDM4E (0.53) | TDP1POLBL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |