Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524315 | 0.82 | CA12 (0.52) | ALDH1A1MAPTKDM4EESR2PTPN1 | |
| SCHEMBL182142 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Hydrochloric Acid SCHEMBL7912933 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL28062236 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL367880 | 0.80 | KDM4E (0.59) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL5127002 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL256719 | 0.79 | TDP1 (0.41) | ALDH1A1MAPTKDM4ETDP1POLB | |
| SCHEMBL19678694 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL8768830 | 0.78 | KDM4E (0.57) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL8541315 | 0.77 | KDM4E (0.52) | ALDH1A1MAPTKDM4ECYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230497-A | Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid | 广东省科学院生物与医学工程研究所 | 2022-03-25 | — | — | CN | claimed |
| CN-117185969-A | Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid | 江苏阿尔法药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114230497-A | Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid | 广东省科学院生物与医学工程研究所 | 2022-03-25 | — | — | CN | disclosed |
| EP-2582665-A1 | AN IMPROVED PROCESS FOR PREPARATION OF AMISULPRIDE | Lupin Limited (IN) | 2013-04-24 | — | — | EP | disclosed |
| US-20130096319-A1 | PROCESS FOR PREPARATION OF AMISULPRIDE | LUPIN LIMITED (IN) | 2013-04-18 | — | — | US | disclosed |
| WO-2011158084-A1 | AN IMPROVED PROCESS FOR PREPARATION OF AMISULPRIDE | LUPIN LIMITED (IN) | 2011-12-22 | — | — | WO | disclosed |
| US-6448257-B1 | TRICYCLIC CARBOXAMIDES CONTAIN A PIPERAZINE OR PIPERIDINE MOIETY; ANTIINFLAMMATORY AGENTS; HEART AND KIDNEY CONDITIONS | SCIOS, INC. | 2002-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096319-A1 | PROCESS FOR PREPARATION OF AMISULPRIDE | TST, TPMT, MSRB3 | ALDH1A1 848/4885MAPT 3876/4885KDM4E 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.