Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28524316

CNc1cnn(Cc2ccc(C(F)(F)F)nc2Cl)c1.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SCD5 Q86SK9 12/20 0.40
SCD O00767 6/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 2/20 0.38
CYP2C8 P10632 2/20 0.38
CYP2B6 P20813 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HPGD P15428 1/20 0.38
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
TRPV1 Q8NER1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21491685 0.82 HSD17B10 (0.38) SCD5KDM4EALDH1A1TRPV1
SCHEMBL28533492 0.79 SCD5 (0.40) SCD5SCDMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL28522972 0.78 TAS2R8 (0.45) SCD5SCDMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL28524210 0.78 SCD5 (0.40) SCD5SCDMEN1KMT2AKDM4E
Trifluoroacetic Acid SCHEMBL28522858 0.76 SCD5 (0.40) SCD5SCDMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL28524435 0.76 MBOAT4 (0.42) SCD5SCDMAPTCYP2C8CYP2B6
Trifluoroacetic Acid SCHEMBL28523073 0.73 SCD5 (0.42) SCD5SCDMAPK1LMNAHTT
SCHEMBL21503568 0.72 MAPT (0.33) KDM4ELMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL30057783 0.72 MAPT (0.33) KDM4ELMNAMAPTALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL28531189 0.70 TAS2R8 (0.40) SCDMAPK1LMNAHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218865-A Pteridinone compounds and uses thereof 沃泰克斯药物股份有限公司 2021-01-12 CN disclosed