Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23323082 | 0.79 | MPO (0.41) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL28909603 | 0.79 | HCRTR2 (0.47) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL20170480 | 0.79 | HCRTR2 (0.47) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL28540055 | 0.79 | HCRTR2 (0.47) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL28521097 | 0.78 | MPO (0.40) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL28533797 | 0.76 | MEN1 (0.40) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL28526259 | 0.76 | MEN1 (0.40) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL23323080 | 0.76 | LTA4H (0.44) | MPOCHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL457401 | 0.76 | HTR2C (0.56) | CHRM5CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL29484307 | 0.76 | HTR2C (0.56) | CHRM5CHRM3CHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |