Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754848 | 0.86 | LMNA (0.39) | ANPEPSRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7076318 | 0.80 | ANPEP (0.40) | ANPEPTSHRTP53ALDH1A1CA1 | |
| SCHEMBL6291617 | 0.80 | ADRB2 (0.31) | — | |
| SCHEMBL10900089 | 0.79 | TSHR (0.52) | ANPEPTSHRTP53SRD5A2ALDH1A1 | |
| SCHEMBL11877213 | 0.79 | TSHR (0.52) | ANPEPTSHRTP53SRD5A2ALDH1A1 | |
| SCHEMBL5133889 | 0.78 | TSHR (0.50) | ANPEPTSHRTP53SRD5A2ALDH1A1 | |
| SCHEMBL3634818 | 0.77 | ANPEP (0.49) | ANPEPTSHRTP53SRD5A2ALDH1A1 | |
| SCHEMBL2593577 | 0.76 | ANPEP (0.61) | ANPEPTSHRTP53SRD5A2ALDH1A1 | |
| SCHEMBL27315463 | 0.76 | ANPEP (0.61) | ANPEPTSHRTP53SRD5A2ALDH1A1 | |
| SCHEMBL9636818 | 0.76 | TSHR (0.48) | ANPEPTSHRTP53SRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906938-B1 | PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS | NICOX SA (FR) | 2010-10-20 | — | — | EP | disclosed |
| US-20090203759-A1 | PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS | NICOX SA (FR) | 2009-08-13 | — | — | US | disclosed |
| EP-1906938-A2 | PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS | NicOx SA (FR) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007012539-A2 | PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS | NICOX S.A. (FR) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203759-A1 | PHARMACEUTICAL FORMULATION OF NITROOXYDERIVATIVES OF NSAIDS | FASN, PTGS1, NOS2 | ANPEP 3719/4885TSHR 2805/4885TP53 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.