Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852492 | 0.92 | ALDH1A1 (0.53) | MAPTPKMLMNAMAPK14ALDH1A1 | |
| SCHEMBL2861253 | 0.89 | MAPT (0.53) | MAPTPKMLMNAMAPK14ALDH1A1 | |
| SCHEMBL2856509 | 0.87 | MAPT (0.48) | MAPTPKMLMNAMAPK14CYP1A2 | |
| SCHEMBL2853248 | 0.86 | MAPT (0.48) | MAPTPKMLMNAMAPK14ALDH1A1 | |
| SCHEMBL2854695 | 0.86 | MAPT (0.50) | MAPTPKMLMNAMAPK14ALDH1A1 | |
| SCHEMBL2852672 | 0.85 | MAPT (0.60) | MAPTPKMLMNAMAPK14CYP1A2 | |
| SCHEMBL2855792 | 0.85 | MEN1 (0.48) | MAPTPKMLMNAALDH1A1MAPK1 | |
| SCHEMBL2853491 | 0.85 | ALDH1A1 (0.55) | MAPTPKMLMNAMAPK14ALDH1A1 | |
| SCHEMBL2860824 | 0.85 | LMNA (0.57) | MAPTPKMLMNAMAPK14ALDH1A1 | |
| SCHEMBL2856893 | 0.83 | MAPT (0.43) | MAPTPKMLMNAMAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |