Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863421 | 0.94 | EPHX1 (0.46) | LMNAPKMMAPTGAAEPHX1 | |
| SCHEMBL2852375 | 0.86 | CCR1 (0.63) | LMNACCR1MAPTGAAMEN1 | |
| SCHEMBL2860461 | 0.85 | TAAR1 (0.54) | LMNAPKMMAPTGAANPC1 | |
| SCHEMBL2857965 | 0.83 | TAAR1 (0.47) | LMNAPKMMAPTGAAADAMTS5 | |
| SCHEMBL2856294 | 0.83 | CCR1 (0.49) | CCR1EPHX1ADAMTS5ABCB1ALDH1A1 | |
| SCHEMBL2850361 | 0.83 | ABCB1 (0.48) | LMNAPKMMAPTGAAMEN1 | |
| SCHEMBL2860099 | 0.83 | TAAR1 (0.46) | LMNAPKMMAPTGAAMEN1 | |
| SCHEMBL2852347 | 0.81 | MAPT (0.46) | LMNAPKMCCR1MAPTGAA | |
| SCHEMBL2856513 | 0.81 | TAAR1 (0.51) | LMNAPKMMAPTGAARAB9A | |
| SCHEMBL2854459 | 0.81 | CCR1 (0.54) | CCR1MAPTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |