Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855394 | 0.91 | ALDH1A1 (0.54) | MAPTALDH1A1MAPK1LMNAPKM | |
| SCHEMBL2850622 | 0.85 | ALDH1A1 (0.57) | MAPTALDH1A1MAPK1LMNAGAA | |
| SCHEMBL2860231 | 0.85 | CNR1 (0.50) | MAPTALDH1A1MAPK1LMNAPKM | |
| SCHEMBL2852322 | 0.83 | MAPT (0.44) | MAPTALDH1A1MAPK1LMNAPKM | |
| SCHEMBL2850782 | 0.83 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAPKMTP53 | |
| SCHEMBL2858522 | 0.83 | CCR1 (0.43) | MAPTALDH1A1LMNAATMCCR1 | |
| SCHEMBL2852547 | 0.81 | LMNA (0.45) | MAPTALDH1A1LMNAPKMGAA | |
| SCHEMBL2856900 | 0.81 | MAPT (0.47) | MAPTLMNAPKMGAAMAPK14 | |
| SCHEMBL2853116 | 0.81 | CNR1 (0.51) | MAPTALDH1A1ABCB1 | |
| SCHEMBL2860461 | 0.80 | TAAR1 (0.54) | MAPTALDH1A1MAPK1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |