Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 13/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860847 | 0.92 | CCR1 (0.55) | CCR1HSP90AA1MAPTNPSR1 | |
| SCHEMBL2854459 | 0.92 | CCR1 (0.54) | CCR1MAPT | |
| SCHEMBL2849956 | 0.87 | CCR1 (0.62) | CCR1HSP90AA1MAPTNPSR1LMNA | |
| SCHEMBL2853390 | 0.86 | CCR1 (0.49) | CCR1HSP90AA1MAPTNPSR1LMNA | |
| SCHEMBL2852547 | 0.86 | LMNA (0.45) | CCR1MAPTLMNAMEN1GAA | |
| SCHEMBL2852107 | 0.85 | CCR1 (0.83) | CCR1HSP90AA1MAPTNPSR1LMNA | |
| SCHEMBL2855497 | 0.85 | MAPT (0.52) | CCR1MAPTLMNA | |
| SCHEMBL2850361 | 0.81 | ABCB1 (0.48) | MAPTLMNAHPGDMEN1GAA | |
| SCHEMBL2852485 | 0.81 | ABCB1 (0.50) | CCR1HSP90AA1MAPTNPSR1LMNA | |
| SCHEMBL2852347 | 0.80 | MAPT (0.46) | CCR1MAPTNPSR1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |