Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504363 | 0.85 | FFAR1 (0.41) | FFAR1KMT2AALDH1A1 | |
| SCHEMBL28899221 | 0.81 | GABBR2 (0.38) | FFAR1PPARGPPARAKMT2ACYP3A4 | |
| SCHEMBL7024971 | 0.81 | FFAR1 (0.80) | FFAR1L3MBTL1LDHAMAPTNPC1 | |
| SCHEMBL27349633 | 0.79 | FFAR1 (0.60) | FFAR1L3MBTL1LDHAMAPTNPC1 | |
| SCHEMBL21199787 | 0.77 | FFAR1 (0.57) | FFAR1L3MBTL1MAPTNPC1NPSR1 | |
| SCHEMBL28769307 | 0.75 | L3MBTL1 (0.68) | FFAR1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL14452889 | 0.75 | FFAR1 (0.51) | FFAR1L3MBTL1MAPTCA1CA2 | |
| SCHEMBL27704468 | 0.72 | L3MBTL1 (0.59) | FFAR1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL27360617 | 0.72 | FFAR1 (0.49) | FFAR1L3MBTL1MAPTKDM4EUSP2 | |
| SCHEMBL27704467 | 0.71 | FFAR1 (0.55) | FFAR1L3MBTL1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294702-B | Chiral alpha-fluorine-containing homoallylamine derivative and preparation method and application thereof | 武汉大学 | 2021-05-04 | — | — | CN | disclosed |
| CN-112279770-A | Chiral alpha-polysubstituted-alpha-fluorine-containing homoallylamine compound, and preparation method and application thereof | 武汉大学 | 2021-01-29 | — | — | CN | disclosed |