Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 9/20 | 0.35 |
| ▸ | NOS3 | P29474 | 6/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523909 | 0.71 | KMT2A (0.41) | KMT2ANOS2NOS3 | |
| SCHEMBL817973 | 0.67 | ACHE (0.46) | KMT2ANOS2NOS3 | |
| SCHEMBL19129357 | 0.67 | KMT2A (0.41) | KMT2ANOS2NOS3 | |
| SCHEMBL28534380 | 0.66 | TAAR1 (0.36) | KMT2A | |
| SCHEMBL11533284 | 0.64 | KMT2A (0.49) | KMT2ANOS2NOS3ALDH1A1MAPT | |
| SCHEMBL11536198 | 0.64 | KMT2A (0.42) | KMT2ANOS2NOS3 | |
| SCHEMBL29073421 | 0.62 | BRD4 (0.44) | MAPT | |
| SCHEMBL13851468 | 0.62 | KMT2A (0.68) | KMT2ANOS2NOS3ALDH1A1MAPT | |
| SCHEMBL16161295 | 0.62 | KMT2A (0.41) | KMT2ANOS2NOS3ALDH1A1MAPT | |
| SCHEMBL7120249 | 0.61 | KMT2A (0.52) | KMT2ANOS2NOS3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836807-A | Oxaspiro compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-10-27 | — | — | CN | disclosed |