Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524561 | 0.79 | LMNA (0.62) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL1395039 | 0.75 | LMNA (1.00) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL375490 | 0.73 | LMNA (0.76) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL28523289 | 0.73 | LMNA (0.65) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL8236728 | 0.72 | LMNA (0.74) | LMNAATG4BRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28533675 | 0.72 | LMNA (0.74) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL1392634 | 0.72 | LMNA (0.92) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL28529715 | 0.71 | ATG4B (0.64) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL4884971 | 0.71 | LMNA (0.90) | LMNAATG4BRAB9AMEN1KMT2A | |
| SCHEMBL10253068 | 0.71 | LMNA (0.77) | LMNAATG4BRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | claimed |
| CN-109503569-B | Thiazole derivative and preparation method and application thereof | 山东大学 | 2021-01-15 | — | — | CN | disclosed |