Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 17/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13276681 | 0.86 | YAP1 (0.54) | YAP1OPRK1KDM4E | |
| SCHEMBL13276979 | 0.85 | YAP1 (0.52) | YAP1OPRK1KDM4E | |
| SCHEMBL13280433 | 0.84 | OPRK1 (0.48) | YAP1OPRK1KDM4E | |
| SCHEMBL4583665 | 0.82 | YAP1 (0.55) | YAP1OPRK1KDM4E | |
| SCHEMBL8833932 | 0.81 | YAP1 (0.62) | YAP1OPRK1KDM4E | |
| SCHEMBL19391535 | 0.81 | YAP1 (0.48) | YAP1OPRK1KDM4EOPRM1OPRD1 | |
| SCHEMBL31535175 | 0.78 | YAP1 (0.50) | YAP1OPRK1KDM4E | |
| SCHEMBL25194622 | 0.77 | KDM4E (0.56) | KDM4E | |
| SCHEMBL15566591 | 0.74 | ABCG2 (0.47) | YAP1OPRK1KDM4E | |
| SCHEMBL13277104 | 0.74 | YAP1 (0.41) | YAP1OPRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573336-B | Benzoheterocycle-formamide-pyridone derivative and preparation method and application thereof | 四川大学 | 2021-01-19 | — | — | CN | disclosed |