SCHEMBL28525833

SCHEMBL28525833

Brc1ccc(Nc2cccc3ccccc23)c2c1-c1ccccc1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 2/20 0.40
CYP3A4 P08684 2/20 0.40
CDC25B P30305 2/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
EGFR P00533 1/20 0.36
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
MAPK1 P28482 1/20 0.35
FADS1 O60427 1/20 0.35
CYP1A2 P05177 3/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19837582 0.82 RAB9A (0.51) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL29780814 0.74 RAB9A (0.47) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL19837479 0.74 RAB9A (0.47) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL17451745 0.71 CA1 (0.40) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL8500339 0.71 HSD17B10 (0.71) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL16276973 0.70 NPC1 (0.63) ALDH1A1HPGDHSD17B10CYP3A4RAB9A
SCHEMBL22189188 0.70 CHRNB2 (0.41) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL30302652 0.70 CHRNB2 (0.41) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL20829121 0.69 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10TP53CYP3A4
SCHEMBL70002 0.69 NPC1 (0.62) ALDH1A1HPGDCYP3A4EGFRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115107391-B Thermosensitive recording medium, laser printing method and laser printing apparatus 株式会社理光 2024-04-19 CN disclosed
CN-117083182-A Thermosensitive recording layer forming liquid, thermosensitive recording medium, production method thereof, and image recording method 株式会社理光 2023-11-17 CN disclosed
CN-115298039-A Thermosensitive recording medium, method of manufacturing thermosensitive recording medium, and article 株式会社理光 2022-11-04 CN disclosed
CN-115107391-A Thermosensitive recording medium, laser printing method and laser printing apparatus 株式会社理光 2022-09-27 CN disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
CN-109328143-B Thermosensitive recording medium and article 株式会社理光 2021-03-23 CN disclosed
CN-110709255-A Recording material and compound 日本曹达株式会社 2020-01-17 CN disclosed