Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474517 | 1.00 | HPGD (0.51) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28532606 | 0.82 | NOTUM (0.49) | MAPTALDH1A1MEN1KMT2ASIRT6 | |
| SCHEMBL30474439 | 0.81 | NOTUM (0.42) | NOTUM | |
| SCHEMBL13884398 | 0.79 | HPGD (0.63) | HPGDMAPTALDH1A1KMT2ASIRT6 | |
| SCHEMBL14938549 | 0.79 | HPGD (0.63) | HPGDMAPTALDH1A1KMT2ASIRT6 | |
| SCHEMBL28547071 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL28532287 | 0.78 | CHRNB2 (0.53) | MAPTALDH1A1MEN1KMT2ASERPINE1 | |
| SCHEMBL21619788 | 0.77 | NOTUM (0.51) | MAPTALDH1A1CYP3A4NOTUMRAB9A | |
| SCHEMBL4256964 | 0.76 | HPGD (0.59) | HPGDMAPTALDH1A1KMT2ASIRT6 | |
| SCHEMBL5388184 | 0.75 | HPGD (0.62) | HPGDMAPTALDH1A1KMT2ASIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |