Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.82 |
| ▸ | HPGDS | O60760 | 3/20 | 0.58 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526144 | 1.00 | CTSL (0.82) | CTSLHPGDSACEPIN1GPR132 | |
| Asperphenamate SCHEMBL29375002 | 0.91 | CTSL (1.00) | CTSLACEPIN1CTRB1ALDH1A1 | |
| SCHEMBL28907567 | 0.84 | CTSL (0.82) | CTSLACEPIN1CTRB1ALDH1A1 | |
| SCHEMBL28907571 | 0.84 | CTSL (0.82) | CTSLACEPIN1CTRB1ALDH1A1 | |
| SCHEMBL28523557 | 0.84 | CTSL (0.86) | CTSLACEPIN1GPR132CTRB1 | |
| SCHEMBL28523556 | 0.84 | CTSL (0.86) | CTSLACEPIN1GPR132CTRB1 | |
| SCHEMBL28592116 | 0.81 | GPR132 (0.70) | HPGDSACEGPR132 | |
| SCHEMBL3497782 | 0.81 | GPR132 (0.70) | HPGDSACEGPR132 | |
| SCHEMBL14005615 | 0.80 | HPGDS (0.58) | CTSLHPGDSPIN1GPR132CTRB1 | |
| SCHEMBL3926900 | 0.80 | CTSL (0.57) | CTSLHPGDSACEGPR132ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112438972-A | Medical application of cathepsin inhibitor | 沈阳药科大学 | 2021-03-05 | — | — | CN | claimed |
| CN-112438972-B | Medical application of cathepsin inhibitor | 沈阳药科大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112438972-A | Medical application of cathepsin inhibitor | 沈阳药科大学 | 2021-03-05 | — | — | CN | disclosed |